ODCs

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6 OMIM references -
6 associated genes
3 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 1

Fibronectin glomerulopathy

2 OMIM references -
1 associated gene
10 signs/symptoms

Neuroblastoma

Fibronectin glomerulopathy

ALK	(UniProt - OMIM)		FN1	(UniProt - OMIM)
HACE1	(UniProt - OMIM)
LIN28B	(UniProt - OMIM)
MYCN	(UniProt - OMIM)
PHOX2B	(UniProt - OMIM)
TOP2A	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TOP2A	(0.63)	FN1

Citations in the biomedical literature:

Neuroblastoma		Fibronectin glomerulopathy
	Synonym(s): - Neural crest tumor - Sympathoblastoma		Synonym(s): - GFND - Glomerulopathy with fibronectin deposits

	Classification (Orphanet): - Rare neurologic disease - Rare oncologic disease		Classification (Orphanet): - Rare genetic disease - Rare renal disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the genitourinary system -

	Epidemiological data: Class of prevalence: 1-5 / 10 000 Average age onset: childhood Average age of death: child / adolescent Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant

	External references: 6 OMIM references - 2 MeSH references: C536408 / D009447		External references: 2 OMIM references - No MeSH references


COMMON SIGNS	- Autosomal dominant inheritance

Neuroblastoma		Fibronectin glomerulopathy
	Very frequent - Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer - Organic acid metabolism anomalies		Very frequent - Chronic arterial hypertension - Edema of the legs / lower limbs - Functional anomalies of the kidney and the urinary tract - Hematuria / microhematuria - Nephrotic syndrome - Proteinuria - Renal failure - Renal glomerular defect / glomerulopathy Occasional - Intracranial / cerebral / meningeal hemorrhage